Circuven Plus contains a synergistic combination of Bilberry, vitamins C and E, B complex, taurine, L-arginine, bitter orange, bioflavonoids, ß-carotenes, and the minerals chromium, zinc, and selenium, which help keep your legs light.MARNYS® Circuven Plus contains the most complete combination of venotonic circulatory ingredients on the market, making it an excellent choice for adults who want to maintain normal circulation and function of the blood vessels and heart, while also protecting against oxidative stress. Directions for use:1 vial, 1-2 times daily with main meals, diluted in a glass of juice. Shake well before use.